ACCELERATE DRUG DISCOVERY FOR HUMAN RARE DISEASES

Protein Expression and Purification

Our team of scientists can work with you to develop the most suitable strategy to express the gene of interest in bacterial and mammalian cells, and then purify the target protein to high degree of purity using several chromatographic techniques.

Enzyme assays and cell culture

We perform patients’ fibroblast cell culture to test therapies of interest, and develop enzyme assays for target enzymes to screen for small molecule chaperones.

Drug Repurposing

We can screen FDA approved drug libraries using purified proteins or patients’ fibroblasts to find molecules that could be applied to treat rare diseases.

Enzyme replacement therapy

We can test protein replacement therapies for rare diseases using patients' cell lines.

To find out more about our capabilities please contact us.